• Degradation Tests
  • Toxicity Tests
  • Genotoxicity
  • Cytotoxicity
  • Chemical informatics
  • Material transport modelling and assessment
  • Analytics

Degradation Tests

according to OECD/DIN/ISO and others:

  • Closed Bottle-Test (OECD 301 D)
  • Manometric Respirometry (OECD 301 F)
  • Zahn-Wellens-Test (OECD 302 B)
  • Waste water treatment plant simulation (OECD 303 A)
  • Water Sediment Test (according to OECD)
  • anaerobic degradation testing (according to DIN EN ISO 117341)
  • Photodegradation
    • UV light
    • sun light
    • photocatalysis

Toxicity Tests

Toxicity in bacteria and algae:

  • modified luminescent bacteria test with Vibrio fischeri 
  • Cell multiplication inhibition test with Pseudomonas putida and Escherichia coli 
  • Long-term contact test with Pseudomonas putida and Bacillus amyloliquefaciens
  • algae toxicity


  • Ames-Test with Salmonella typhimurium TA 98/TA 100
  • Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
  • Mikronucleus-Test with CHO-Cells by FACS-Analysis


  • Resazurin-Assay

Chemical informatics

Structure property relationships (QSAR), also in REACH-Quality

  • Calculation of physicochemical properties of molecules
  • Calculation of quantum chemical parameters of molecules
  • Calculation of toxicity and eco-toxicity
  • Calculation of mutagenicity according to ICHM7 in U.S. FDA/EMA-approved quality
  • Calculation of the biological degradation
  • Predictions for metabolites and degradation products (mammalia, bacteria, light)


  • prediction of pharmaceutical effects, in combination with QSAR (drug likeness)

Material transport modelling and assessment

  • Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
  • Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
  • Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
  • Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
  • River channel modelling of water, sediment, phosphorus, pesticide and transformation products discharge (ZIN-Sed, MOHID Stream)
  • Scenario modelling and assessment
  • System analysis and management assessment
  • Integrated water resources management


  • LC-MS/MS (Liquid chromatography coupled to ion trap mass spectrometry and
    • high-resolution mass spectrometry (Orbitrap)
    • low resolutionary (Ion Trap, Triple Quad)
  • NMR Spinsolve Carbon (Magritek) mit 42,5 MHz 1H und 10,8 MHz 13C
  • HPLC with UV and fluorescence detection
  • Gas chromatography coupled to mass spectrometry
  • Ion chromatography
  • IR Spectrometers
  • UV Spectrometers