Around and in the Laboratory

according to OECD/DIN/ISO and others:
 

• Closed Bottle-Test (OECD 301 D)
• Manometric Respirometry (OECD 301 F)
• Zahn-Wellens-Test (OECD 302 B)
• Waste water treatment plant simulation (OECD 303 A)
• Water Sediment Test (according to OECD)
• anaerobic degradation testing (according to DIN EN ISO 117341)
• Photodegradation
  • UV light
  • sun light
  • photocatalysis

Toxicity in bacteria and algae:

• modified luminescent bacteria test with Vibrio fischeri 
• Cell multiplication inhibition test with Pseudomonas putida and Escherichia coli 
• Long-term contact test with Pseudomonas putida and Bacillus amyloliquefaciens
• algae toxicity

• Ames-Test with Salmonella typhimurium TA 98/TA 100
• Umu-Test with Salmonella typhimurium TA 1535/ psK 1002
• Mikronucleus-Test with CHO-Cells by FACS-Analysis

• Resazurin-Assay

Structure property relationships (QSAR), also in REACH-Quality

• Calculation of physicochemical properties of molecules
• Calculation of quantum chemical parameters of molecules
• Calculation of toxicity and eco-toxicity
• Calculation of mutagenicity according to ICHM7 in U.S. FDA/EMA-approved quality
• Calculation of the biological degradation
• Predictions for metabolites and degradation products (mammalia, bacteria, light)

   Docking

• prediction of pharmaceutical effects, in combination with QSAR (drug likeness)

• Spatio-temporal analysis of discharge and water quality (R-Statistics, SigmaPlot, ArcGIS)
• Assessment of water quality by combined water quality and quantity indices (WQI, WQQI, WAI)
• Water quality modelling in lakes and reservoirs in 1D, 2D and 3D (LAC, MOHID Water, Ce-qual)
• Catchment modelling of hydrology, erosion and sedimenttransport, phosphorus discharge, pesticides and transformation product discharge (ZIN-Sed, MOHID Land, reservoir models)
• River channel modelling of water, sediment, phosphorus, pesticide and transformation products discharge (ZIN-Sed, MOHID Stream)
• Scenario modelling and assessment
• System analysis and management assessment
• Integrated water resources management

• LC-MS/MS (Liquid chromatography coupled to ion trap mass spectrometry and
  • high-resolution mass spectrometry (Orbitrap)
  • low resolutionary (Ion Trap, Triple Quad)
• NMR Spinsolve Carbon (Magritek) mit 42,5 MHz 1H und 10,8 MHz 13C
• HPLC with UV and fluorescence detection
• Gas chromatography coupled to mass spectrometry
• Ion chromatography
• IR Spectrometers
• UV Spectrometers